MD, Cornell University Medical College, 1977

Phone: (732) 235-5381
Fax: (732) 235-4990

email: diciccem@umdnj.edu

Research interests:
Cell cycle regulation by mitogenic and trophic signals during peripheral and central neurogenesis. Studies examine regulation by growth factors and neuropeptides in cell culture and in in vivo model systems, as well as after genetic manipulation by transfection, electroporation and gene deletion.

Selected Publications 1

Suh, J., Lu, N., Nicot, A., Tatsuno, I. and DiCicco-Bloom, E. (2001) PACAP is an anti-mitogenic signal in developing cerebral cortex. Nature Neuroscience, 4:123-124.

Cheng, Y., Tao, Y., Black, I.B., and DiCicco-Bloom, E. (2001) A single peripheral injection of basic fibroblast growth factor (bFGF) stimulates granule cell production and increases cerebellar growth in new born rats. J. Neurobiol. 46:220-229.

Nicot, A. and DiCicco-Bloom, E. (2001) Regulation of neuroblast mitosis is determined by PACAP receptor isoform expression. Proc. Natl. Acad. Sci. (USA), 98:4758-4763.

Cheng, T., Black, I.B. and DiCicco-Bloom, E. (2002) Hippocampal granule neuron production and population size are regulated by levels of bFGF. Eur. J. Neurosci., 15:3-12.

Carey, R.G., Li, B. and DiCicco-Bloom, E. (2002) Pituitary adenylate cyclase activating polypeptide anti-mitogenic signaling in cerebral cortical progenitors is regulated by p57Kip2-dependent CDK2 activity. J. Neurosci., 22:1583-1591.

Nicot, A., Lelivre, V., Tam, J., Waschek, J.A. and DiCicco-Bloom, E.(2002) Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) and Sonic Hedgehog (Shh) Interact to Control Cerebellar Granule Precursor Cell Proliferation. J. Neurosci. 22:9244-54.

DiCicco-Bloom, E., Lelivre, V., Zhou, X., Rodriguez, W., Tam, J., and Waschek, J.A. (2004) Embryonic expression and multi-functional actions of the natriuretic peptides and receptors in the developing nervous system. Dev. Biol. 271:161-75.

Nicot, A., Otto, T., Brabet, P., and DiCicco-Bloom, E. (2004) Altered social behavior in pituitary adenylate cyclase-activating polypeptide (PACAP) type I receptor deficient mice. J. Neurosci. 24:8786-8795.